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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dopamine D1 receptor' and Ligand = 'BDBM337368'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D1 receptor


(Homo sapiens (Human))
BDBM337368
PNG
((+)-5-[4-(2,3-dihydrofuro[3,2-c]pyridin-4-yloxy)-2...)
Show SMILES Cc1cc(Oc2nccc3OCCc23)ccc1-c1c(C)n[nH]c(=O)c1C
Show InChI InChI=1S/C20H19N3O3/c1-11-10-14(26-20-16-7-9-25-17(16)6-8-21-20)4-5-15(11)18-12(2)19(24)23-22-13(18)3/h4-6,8,10H,7,9H2,1-3H3,(H,23,24)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
12.6n/an/an/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...


US Patent US9745317 (2017)


Article DOI: 10.1021/jm049187l
More data for this
Ligand-Target Pair