BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dopamine D1 receptor' and Ligand = 'BDBM337373'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D1 receptor


(Homo sapiens (Human))
BDBM337373
PNG
(5-[4-(6, 7-Dihydro-5H-pyrrolo[2, 3-d]pyrimidin-4-y...)
Show SMILES COc1ccc(CN2CCc3c2ncnc3Oc2ccc(cc2)-c2c(C)nn(C3CCCCO3)c(=O)c2C)cc1
Show InChI InChI=1S/C31H33N5O4/c1-20-28(21(2)34-36(31(20)37)27-6-4-5-17-39-27)23-9-13-25(14-10-23)40-30-26-15-16-35(29(26)32-19-33-30)18-22-7-11-24(38-3)12-8-22/h7-14,19,27H,4-6,15-18H2,1-3H3
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
60.4n/an/an/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...


US Patent US9745317 (2017)


Article DOI: 10.1021/jm049187l
BindingDB Entry DOI: 10.7270/Q2W95CBQ
More data for this
Ligand-Target Pair