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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dopamine D1 receptor' and Ligand = 'BDBM337377'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D1 receptor


(Homo sapiens (Human))
BDBM337377
PNG
(4,6-Dimethyl-5-[2-methyl-4-(1,2,3,4-tetrahydro-1,6...)
Show SMILES Cc1cc(Oc2nccc3N(Cc4ccccc4)CCCc23)ccc1-c1c(C)nn(C2CCCCO2)c(=O)c1C
Show InChI InChI=1S/C33H36N4O3/c1-22-20-26(14-15-27(22)31-23(2)33(38)37(35-24(31)3)30-13-7-8-19-39-30)40-32-28-12-9-18-36(29(28)16-17-34-32)21-25-10-5-4-6-11-25/h4-6,10-11,14-17,20,30H,7-9,12-13,18-19,21H2,1-3H3
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
18.1n/an/an/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...


US Patent US9745317 (2017)

More data for this
Ligand-Target Pair