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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dopamine D1 receptor' and Ligand = 'BDBM337389'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D1 receptor


(Homo sapiens (Human))
BDBM337389
PNG
(US9745317, 27)
Show SMILES Cc1c(-c2ccc(Oc3ncnc4NCCc34)cc2)n(C)c(=O)[nH]c1=O
Show InChI InChI=1S/C18H17N5O3/c1-10-14(23(2)18(25)22-16(10)24)11-3-5-12(6-4-11)26-17-13-7-8-19-15(13)20-9-21-17/h3-6,9H,7-8H2,1-2H3,(H,19,20,21)(H,22,24,25)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
44.4n/an/an/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...


US Patent US9745317 (2017)


Article DOI: 10.1021/jm049187l
More data for this
Ligand-Target Pair