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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Dopamine D1 receptor' and Ligand = 'BDBM337390'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dopamine D1 receptor


(Homo sapiens (Human))
BDBM337390
PNG
(US9745317, 28)
Show SMILES Cc1c(-c2ccc(Oc3ncnc4CCCc34)cc2)n(C)c(=O)[nH]c1=O
Show InChI InChI=1S/C19H18N4O3/c1-11-16(23(2)19(25)22-17(11)24)12-6-8-13(9-7-12)26-18-14-4-3-5-15(14)20-10-21-18/h6-10H,3-5H2,1-2H3,(H,22,24,25)
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
Article
US Patent
202n/an/an/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...


US Patent US9745317 (2017)


Article DOI: 10.1021/jm049187l
BindingDB Entry DOI: 10.7270/Q2W95CBQ
More data for this
Ligand-Target Pair