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Found 3 Enz. Inhib. hit(s) with Target = 'Dual specificity protein kinase TTK' and Ligand = 'BDBM413450'
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM413450(7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridi...)
Affinity DataIC50:  5.01E+3nMAssay Description:The inhibitory activity of compounds against AURKA, AURKB, JAK1, JAK2 and JAK3 was determined in Z′-LYTEŽ assays run by ThermoFisher Scientific...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM413450(7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridi...)
Affinity DataIC50:  5.01E+3nMAssay Description:The inhibitory activity of compounds against TTK was determined in a LanthaScreenŽ Eu Kinase Binding assay run by ThermoFisher Scientific as part of ...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM413450(7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridi...)
Affinity DataIC50:  5.01E+3nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to recombinant human full-length GST-tagged TTK expressed in baculovirus expression system measur...More data for this Ligand-Target Pair
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In DepthDetails ArticlePubMed