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Found 1 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM129947'
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM129947(US8815926, 228)
Affinity DataIC50:  0.0800nMAssay Description:The inhibition of p53-MDM2 and p53-MDM4 interactions is measured by time resolved fluorescence energy transfer (TR-FRET). Fluorescence energy transfe...More data for this Ligand-Target Pair
In DepthDetails US Patent