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Found 1 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM162069'
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM162069(US9051279, 79)
Affinity DataIC50:  1.60nMAssay Description:The inhibition of p53-Hdm2 and p53-Hdm4 interactions is measured by time resolved fluorescence energy transfer (TR-FRET). Fluorescence energy transfe...More data for this Ligand-Target Pair
In DepthDetails US Patent