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Found 1 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM31299'
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM31299(1,4-benzodiazepine-2,5-dione scaffold, 25)
Affinity DataIC50:  1.90E+4nMpH: 7.5 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed