Found 2 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM31314'
Affinity DataIC50: 546nMpH: 7.4 T: 2°CAssay Description:Test compound was incubated for 15 minutes with 30 nM peptide fluorescein-FMDYWEGLN (Fl 9mer) and 120 nM (glycine-HDM2 17-125) in assay buffer. The p...More data for this Ligand-Target Pair
Affinity DataIC50: 704nMAssay Description:Inhibition of p53 protein binding to MDM2 (unknown origin)More data for this Ligand-Target Pair