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Found 1 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM50448959'
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50448959(CHEMBL3125697 | US9296736, 350 | US9593129, Exampl...)
Affinity DataIC50:  0.200nMAssay Description:Binding affinity to human GST-thrombin-tagged MDM2 assessed as inhibition of interaction with human p53 after 1 hr by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed