Found 2 Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM50448969'
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
International Institute For Translational Chinese Medicine
Curated by ChEMBL
International Institute For Translational Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of p53-MDM2 interaction (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
International Institute For Translational Chinese Medicine
Curated by ChEMBL
International Institute For Translational Chinese Medicine
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Binding affinity to human GST-thrombin-tagged MDM2 assessed as inhibition of interaction with human p53 after 1 hr by HTRF assayMore data for this Ligand-Target Pair