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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'EBifunctional epoxide hydrolase 2' and Ligand = 'BDBM50002341'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
EBifunctional epoxide hydrolase 2


(Homo sapiens (Human))
BDBM50002341
PNG
(CHEMBL442384)
Show SMILES Nc1nc2ccc(cc2s1)C(F)(F)F
Show InChI InChI=1S/C8H5F3N2S/c9-8(10,11)4-1-2-5-6(3-4)14-7(12)13-5/h1-3H,(H2,12,13)
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Article
PubMed
n/an/a 4.90E+4n/an/an/an/an/an/a



Astellas Pharma Inc

Curated by ChEMBL


Assay Description
Inhibition of human full-length C-terminal His6-tagged sEH expressed in Escherichia coli BL21(DE3) cells using PHOME as substrate incubated with enzy...


Bioorg Med Chem 22: 2427-34 (2014)


Article DOI: 10.1016/j.bmc.2014.03.001
BindingDB Entry DOI: 10.7270/Q2NV9KRF
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)