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Found 1 hit Enz. Inhib. hit(s) with Target = 'EBifunctional epoxide hydrolase 2' and Ligand = 'BDBM50068108'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
EBifunctional epoxide hydrolase 2


(Homo sapiens (Human))
BDBM50068108
PNG
(CHEMBL3402236)
Show SMILES Oc1cnn(c1)-c1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C10H7F3N2O/c11-10(12,13)7-2-1-3-8(4-7)15-6-9(16)5-14-15/h1-6,16H
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Article
PubMed
n/an/a 5.20E+4n/an/an/an/an/an/a



Astellas Pharma Inc

Curated by ChEMBL


Assay Description
Inhibition of C-terminal His6-tagged full-length human soluble epoxide hydrolase expressed in Escherichia coli BL21(DE3) cells pre-incubated for 15 m...


Bioorg Med Chem 23: 2310-7 (2015)


Article DOI: 10.1016/j.bmc.2015.03.083
BindingDB Entry DOI: 10.7270/Q2DV1MKD
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)