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Found 5 Enz. Inhib. hit(s) with Target = 'Endothelin-1 receptor' and Ligand = 'BDBM50066391'
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50066391((2S,3R,4S)-1-Dibutylcarbamoylmethyl-2-(2,2-dimethy...)
Affinity DataKi:  0.460nMAssay Description:Tested for binding affinity for human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from chinese hamster ovary cells(CHO)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50066391((2S,3R,4S)-1-Dibutylcarbamoylmethyl-2-(2,2-dimethy...)
Affinity DataKi:  0.460nMAssay Description:Binding affinity against endothelin A receptor in MMQ cells in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50066391((2S,3R,4S)-1-Dibutylcarbamoylmethyl-2-(2,2-dimethy...)
Affinity DataIC50:  0.490nMAssay Description:Inhibitory activity against human endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50066391((2S,3R,4S)-1-Dibutylcarbamoylmethyl-2-(2,2-dimethy...)
Affinity DataIC50:  0.560nMAssay Description:Binding affinity for endothelin A receptor by measuring its ability to displace [125I]-ET-1 from prolactin secreting rat pituitary cells(MMQ)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50066391((2S,3R,4S)-1-Dibutylcarbamoylmethyl-2-(2,2-dimethy...)
Affinity DataIC50:  2.49E+4nMAssay Description:Tested for binding affinity for human Endothelin A receptor by measuring its ability to displace [125I]-ET-1 from chinese hamster ovary cells(CHO)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed