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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ephrin type-B receptor 3 (EPHB3)' and Ligand = 'BDBM50311298'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ephrin type-B receptor 3 (EPHB3)


(Homo sapiens (Human))
BDBM50311298
PNG
(4-chloro-N-(2-chlorophenyl)pyrazolo[1,5-a]pyridine...)
Show SMILES Clc1ccccc1NC(=O)c1cnn2cccc(Cl)c12
Show InChI InChI=1S/C14H9Cl2N3O/c15-10-4-1-2-6-12(10)18-14(20)9-8-17-19-7-3-5-11(16)13(9)19/h1-8H,(H,18,20)
PDB
MMDB

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UniProtKB/SwissProt

B.MOAD
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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...


Bioorg Med Chem Lett 19: 6122-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.010
BindingDB Entry DOI: 10.7270/Q2T43T66
More data for this
Ligand-Target Pair