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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ephrin type-B receptor 3 (EPHB3)' and Ligand = 'BDBM50311306'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ephrin type-B receptor 3 (EPHB3)


(Homo sapiens (Human))
BDBM50311306
PNG
(CHEMBL1078214 | N-(2-chlorophenyl)-5-(piperidin-1-...)
Show SMILES Clc1ccccc1NC(=O)c1cnn2ccc(cc12)N1CCCCC1
Show InChI InChI=1S/C19H19ClN4O/c20-16-6-2-3-7-17(16)22-19(25)15-13-21-24-11-8-14(12-18(15)24)23-9-4-1-5-10-23/h2-3,6-8,11-13H,1,4-5,9-10H2,(H,22,25)
PDB
MMDB

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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 63n/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...


Bioorg Med Chem Lett 19: 6122-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.010
BindingDB Entry DOI: 10.7270/Q2T43T66
More data for this
Ligand-Target Pair