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Found 2 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM21896'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM21896(4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H-imidazol...)
Affinity DataIC50:  30nMAssay Description:Inhibition of EGFR kinase autophosphorylation in A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM21896(4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H-imidazol...)
Affinity DataIC50:  30nMAssay Description:EGFR kinase activity was assayed using poly(Glu4-Tyr) as a substrate. The phosphorylation of tyrosine residue was detected by an ELISA. IC50 calculat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed