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Found 2 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM332539'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Arromax Pharmatech

Curated by ChEMBL
LigandPNGBDBM332539((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-ethox...)
Affinity DataIC50:  0.690nMAssay Description:Inhibition of recombinant human GST-tagged EGFR catalytic domain (668 to 1210 residues) expressed in baculovirus expression system using TK-biotin pe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Arromax Pharmatech

Curated by ChEMBL
LigandPNGBDBM332539((E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(2-ethox...)
Affinity DataIC50:  0.699nMAssay Description:The kinase analysis in vitro was performed using the HTRF kinEASE TK kit of Invitrogen Co., the procedure steps were carried out according to instruc...More data for this Ligand-Target Pair
In DepthDetails US Patent