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Found 2 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM4339'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University Of Jerusalem

LigandPNGBDBM4339((3,4-Dihydroxybenzylidene)malononitrile | 2-[(3,4-...)
Affinity DataKi:  1.10E+4nM ΔG°:  -28.0kJ/mole IC50:  3.50E+4nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University Of Jerusalem

LigandPNGBDBM4339((3,4-Dihydroxybenzylidene)malononitrile | 2-[(3,4-...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of EGFR autophosphorylationChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed