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Found 3 Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor' and Ligand = 'BDBM50183388'
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183388(CHEMBL3818015)
Affinity DataIC50:  0.380nMAssay Description:Inhibition of recombinant human EGFR L858R mutant expressed in baculovirus infected insect cells preincubated for 5 mins followed by ATP addition for...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183388(CHEMBL3818015)
Affinity DataIC50:  0.470nMAssay Description:Inhibition of wild type human EGFR preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50183388(CHEMBL3818015)
Affinity DataIC50:  126nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) preincubated for 5 mins followed by ATP addition for 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed