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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Epidermal growth factor receptor (T790M/L858R) ' and Ligand = 'BDBM285865'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Epidermal growth factor receptor (T790M/L858R)


(Homo sapiens (Human))
BDBM285865
PNG
(US10081606, Compound I-14 | US9765038, Compound I-...)
Show SMILES COc1cccc(Nc2ncc(Br)c(Nc3cccc(NC(=O)C=C)c3)n2)c1OC
Show InChI InChI=1S/C21H20BrN5O3/c1-4-18(28)24-13-7-5-8-14(11-13)25-20-15(22)12-23-21(27-20)26-16-9-6-10-17(29-2)19(16)30-3/h4-12H,1H2,2-3H3,(H,24,28)(H2,23,25,26,27)
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.5n/an/an/an/an/an/a



Celgene CAR LLC

US Patent




US Patent US9765038 (2017)

More data for this
Ligand-Target Pair