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Found 2 Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM306723'
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM306723(N1-(3,5-difluoro-4-((1R,3R)-2-((1-fluorocyclopropy...)
Affinity DataIC50:  0.220nMAssay Description:The ability of compounds to down-regulate Estrogen Receptor (ER) numbers was assessed in a cell based immuno-fluorescence assay using the MCF-7 human...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM306723(N1-(3,5-difluoro-4-((1R,3R)-2-((1-fluorocyclopropy...)
Affinity DataIC50:  4.80nMAssay Description:Compounds were dosed directly from a compound source microplate containing serially diluted compound (4 wells containing 10 mM, 0.1 mM, 1 mM and 10 n...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent