Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM50099586'
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099586(2-(4-Hydroxy-phenyl)-3-methyl-1-(6-pyrrolidin-1-yl...)
Affinity DataIC50:  25nMAssay Description:In vitro inhibition of [3H]-17-beta-estradiol binding to human estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099586(2-(4-Hydroxy-phenyl)-3-methyl-1-(6-pyrrolidin-1-yl...)
Affinity DataIC50:  69nMAssay Description:In vitro antagonist effect on estrogen receptor alpha transcriptional activation in MCF-7 cells against 10 pM 17-beta-estradiolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed