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Found 3 Enz. Inhib. hit(s) with Target = 'Estrogen receptor' and Ligand = 'BDBM50121602'
TargetEstrogen receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50121602(4-[2-(4-{[3-(4-Fluoro-phenyl)-propyl]-methyl-amino...)
Affinity DataKi:  380nMAssay Description:In vitro binding affinity towards human Estrogen receptor alpha using [3H]-17-beta-estradiol as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50121602(4-[2-(4-{[3-(4-Fluoro-phenyl)-propyl]-methyl-amino...)
Affinity DataIC50:  240nMAssay Description:In vitro inhibition of transcriptional activation induced by 1 nM 17-beta estradiol in T47D cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50121602(4-[2-(4-{[3-(4-Fluoro-phenyl)-propyl]-methyl-amino...)
Affinity DataEC50:  200nMAssay Description:Agonist effect on transcriptional activation in T47D cells expressing estrogen receptor alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed