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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Estrogen receptor alpha D538G' and Ligand = 'BDBM263673'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Estrogen receptor alpha D538G


(Homo sapiens (Human))
BDBM263673
PNG
(6-(2-fluoro- 4-hydroxy- phenyl)-5- [4-[(3S)-1- (3-...)
Show SMILES Oc1ccc(c(F)c1)C1=C(c2ccc(O[C@H]3CCN(CCCF)C3)cc2)c2ccc(O)cc2CCC1
Show InChI InChI=1S/C30H31F2NO3/c31-14-2-15-33-16-13-25(19-33)36-24-9-5-20(6-10-24)30-26-11-7-22(34)17-21(26)3-1-4-28(30)27-12-8-23(35)18-29(27)32/h5-12,17-18,25,34-35H,1-4,13-16,19H2/t25-/m0/s1
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5n/an/an/an/a7.425



SANOFI

US Patent


Assay Description
It is a competition assay, where binding of a test compound to a complex comprised of (i) His6-ERα298-554 protein representing ERα ligand-b...


US Patent US9714221 (2017)

More data for this
Ligand-Target Pair