Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) with Target = 'Estrogen-related receptor gamma' and Ligand = 'BDBM22438'
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Gsk

LigandPNGBDBM22438(4-Hydroxy-benzoic acid (4-isopropyl-benzylidene)-h...)
Affinity DataEC50:  1.30E+3nMpH: 7.0 T: 2°CAssay Description:Recruitment of the RIP140 NR-box peptide to the ERRgamma ligand binding domain was assayed by FRET detection. Proteins were set up in a one to one ra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Gsk

LigandPNGBDBM22438(4-Hydroxy-benzoic acid (4-isopropyl-benzylidene)-h...)
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at Gal4 fused ERRgamma-LBD (unknown origin) expressed in HEK293T cells after 20 hrs by UAS-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Gsk

LigandPNGBDBM22438(4-Hydroxy-benzoic acid (4-isopropyl-benzylidene)-h...)
Affinity DataEC50:  600nMAssay Description:Agonist activity at human N-terminal alphaHis-SUMO-tagged ERRgamma-LBD (229 to 458 residues) expressed in Escherichia coli BL21 gold (DE3) cells asse...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Gsk

LigandPNGBDBM22438(4-Hydroxy-benzoic acid (4-isopropyl-benzylidene)-h...)
Affinity DataKd:  5.00E+3nMAssay Description:Binding affinity to ERRgamma (unknown origin) at 20 degC by isothermal titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed