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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Eukaryotic elongation factor 2 kinase' and Ligand = 'BDBM293927'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM293927
PNG
(US10106552, Compound 2)
Show SMILES CC1(C)CCc2nc3sc(C(N)=O)c(N)c3c(-c3ccc(Cl)o3)c2C1
Show InChI InChI=1S/C18H18ClN3O2S/c1-18(2)6-5-9-8(7-18)12(10-3-4-11(19)24-10)13-14(20)15(16(21)23)25-17(13)22-9/h3-4H,5-7,20H2,1-2H3,(H2,21,23)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.10E+3n/an/an/an/an/an/a



Longevica Pharmaceuticals, Inc.

US Patent


Assay Description
To determine the IC50 of compounds of the invention, recombinant eEF2K was diluted in an assay buffer in the presence of calmodulin, a calcium-bindin...


US Patent US10106552 (2018)

More data for this
Ligand-Target Pair