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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Eukaryotic elongation factor 2 kinase' and Ligand = 'BDBM293942'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Eukaryotic elongation factor 2 kinase


(Homo sapiens (Human))
BDBM293942
PNG
(US10106552, Compound 17)
Show SMILES CC1(C)CCc2c1nc1sc(C(N)=O)c(N)c1c2-c1ccoc1
Show InChI InChI=1S/C17H17N3O2S/c1-17(2)5-3-9-10(8-4-6-22-7-8)11-12(18)13(15(19)21)23-16(11)20-14(9)17/h4,6-7H,3,5,18H2,1-2H3,(H2,19,21)
PDB

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KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.10E+3n/an/an/an/an/an/a



Longevica Pharmaceuticals, Inc.

US Patent


Assay Description
To determine the IC50 of compounds of the invention, recombinant eEF2K was diluted in an assay buffer in the presence of calmodulin, a calcium-bindin...


US Patent US10106552 (2018)

More data for this
Ligand-Target Pair