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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'FLT3(D835Y)' and Ligand = 'BDBM319752'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
FLT3(D835Y)


(Homo sapiens (Human))
BDBM319752
PNG
(US10174013, Example 1A | US10174013, Example 1X | ...)
Show SMILES CCn1c(nc2c(c(Br)c(Br)cc12)[N+]([O-])=O)N1CCNCC1
Show InChI InChI=1S/C13H15Br2N5O2/c1-2-19-9-7-8(14)10(15)12(20(21)22)11(9)17-13(19)18-5-3-16-4-6-18/h7,16H,2-6H2,1H3
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/a 46n/an/an/an/an/a



SELVITA S.A.

US Patent


Assay Description
Selected compounds were also tested for their binding properties against FLT3 kinase mutants using suitable in vitro assays (performed according to s...


US Patent US10174013 (2019)

More data for this
Ligand-Target Pair