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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Factor D' and Ligand = 'BDBM340204'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Factor D


(Homo sapiens (Human))
BDBM340204
PNG
((2S,4R)-N1-(1-acetyl- 1H-indol-3-yl)-N2-(3- chloro...)
Show SMILES CC(=O)n1cc(NC(=O)N2C[C@H](F)C[C@H]2C(=O)NS(=O)(=O)c2cccc(Cl)c2F)c2ccccc12
Show InChI InChI=1S/C22H19ClF2N4O5S/c1-12(30)28-11-16(14-5-2-3-7-17(14)28)26-22(32)29-10-13(24)9-18(29)21(31)27-35(33,34)19-8-4-6-15(23)20(19)25/h2-8,11,13,18H,9-10H2,1H3,(H,26,32)(H,27,31)/t13-,18+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



Achillion Pharmaceuticals

US Patent


Assay Description
Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...


US Patent US9758537 (2017)

More data for this
Ligand-Target Pair