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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Factor D' and Ligand = 'BDBM340206'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Factor D


(Homo sapiens (Human))
BDBM340206
PNG
((R)-N2-(1-acetyl-1H- indol-3-yl)-N1-(3- chloro-2- ...)
Show SMILES CC(=O)n1cc(NC(=O)[C@H]2CCCN2C(=O)NCc2cccc(Cl)c2F)c2ccccc12
Show InChI InChI=1S/C23H22ClFN4O3/c1-14(30)29-13-18(16-7-2-3-9-19(16)29)27-22(31)20-10-5-11-28(20)23(32)26-12-15-6-4-8-17(24)21(15)25/h2-4,6-9,13,20H,5,10-12H2,1H3,(H,26,32)(H,27,31)/t20-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



Achillion Pharmaceuticals

US Patent


Assay Description
Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...


US Patent US9758537 (2017)

More data for this
Ligand-Target Pair