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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Factor D' and Ligand = 'BDBM340215'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Factor D


(Homo sapiens (Human))
BDBM340215
PNG
((2S,3R)-1-(2-(3-acetyl- 1H-indol-1-yl)acetyl)- N-(...)
Show SMILES CC(=O)c1cn(CC(=O)N2CC[C@@H](OCC3CC3)[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc12
Show InChI InChI=1S/C28H29ClFN3O4/c1-17(34)21-14-32(23-8-3-2-6-20(21)23)15-25(35)33-12-11-24(37-16-18-9-10-18)27(33)28(36)31-13-19-5-4-7-22(29)26(19)30/h2-8,14,18,24,27H,9-13,15-16H2,1H3,(H,31,36)/t24-,27+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<1.00E+3n/an/an/an/an/an/a



Achillion Pharmaceuticals

US Patent


Assay Description
Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...


US Patent US9758537 (2017)

More data for this
Ligand-Target Pair