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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Factor D' and Ligand = 'BDBM340220'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Factor D


(Homo sapiens (Human))
BDBM340220
PNG
((1R,2R)-N1-(1- carbamoyl-1H-indol-3- yl)-N2-(3-chl...)
Show SMILES NC(=O)n1cc(NC(=O)[C@@H]2CCC[C@H]2C(=O)NCc2cccc(Cl)c2F)c2ccccc12
Show InChI InChI=1S/C23H22ClFN4O3/c24-17-9-3-5-13(20(17)25)11-27-21(30)14-7-4-8-15(14)22(31)28-18-12-29(23(26)32)19-10-2-1-6-16(18)19/h1-3,5-6,9-10,12,14-15H,4,7-8,11H2,(H2,26,32)(H,27,30)(H,28,31)/t14-,15-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



Achillion Pharmaceuticals

US Patent


Assay Description
Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...


US Patent US9758537 (2017)

More data for this
Ligand-Target Pair