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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Factor D' and Ligand = 'BDBM340234'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Factor D


(Homo sapiens (Human))
BDBM340234
PNG
((2S,4R)-N-(3-chloro-2- fluorobenzyl)-4-fluoro- 1-(...)
Show SMILES F[C@@H]1C[C@H](N(C1)C(=O)Cn1c2CCCC(=O)c2c2ccccc12)C(=O)NCc1cccc(Cl)c1F
Show InChI InChI=1S/C26H24ClF2N3O3/c27-18-7-3-5-15(25(18)29)12-30-26(35)21-11-16(28)13-32(21)23(34)14-31-19-8-2-1-6-17(19)24-20(31)9-4-10-22(24)33/h1-3,5-8,16,21H,4,9-14H2,(H,30,35)/t16-,21+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<1.00E+3n/an/an/an/an/an/a



Achillion Pharmaceuticals

US Patent


Assay Description
Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...


US Patent US9758537 (2017)

More data for this
Ligand-Target Pair