BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Factor D' and Ligand = 'BDBM340248'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Factor D


(Homo sapiens (Human))
BDBM340248
PNG
((2S,4R)-1-(6- acetamidonicotinoyl)- N-(3-chloro-2-...)
Show SMILES CC(=O)Nc1ccc(cn1)C(=O)N1C[C@H](F)C[C@H]1C(=O)NCc1cccc(Cl)c1F
Show InChI InChI=1S/C20H19ClF2N4O3/c1-11(28)26-17-6-5-13(9-24-17)20(30)27-10-14(22)7-16(27)19(29)25-8-12-3-2-4-15(21)18(12)23/h2-6,9,14,16H,7-8,10H2,1H3,(H,25,29)(H,24,26,28)/t14-,16+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



Achillion Pharmaceuticals

US Patent


Assay Description
Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...


US Patent US9758537 (2017)

More data for this
Ligand-Target Pair