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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Factor D' and Ligand = 'BDBM340251'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Factor D


(Homo sapiens (Human))
BDBM340251
PNG
((2S,4R)-N2-(3-chloro- 2-fluorobenzyl)-N1-(1- (cycl...)
Show SMILES F[C@@H]1C[C@H](N(C1)C(=O)Nc1cn(C(=O)C2CC2)c2ccccc12)C(=O)NCc1cccc(Cl)c1F
Show InChI InChI=1S/C25H23ClF2N4O3/c26-18-6-3-4-15(22(18)28)11-29-23(33)21-10-16(27)12-32(21)25(35)30-19-13-31(24(34)14-8-9-14)20-7-2-1-5-17(19)20/h1-7,13-14,16,21H,8-12H2,(H,29,33)(H,30,35)/t16-,21+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<1.00E+3n/an/an/an/an/an/a



Achillion Pharmaceuticals

US Patent


Assay Description
Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...


US Patent US9758537 (2017)

More data for this
Ligand-Target Pair