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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Factor D' and Ligand = 'BDBM340258'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Factor D


(Homo sapiens (Human))
BDBM340258
PNG
(US9758537, Compound 61 | diethyl 3-(((2S,4R)-1- (2...)
Show SMILES CCOP(=O)(OCC)c1cc(Cl)c(F)c(CNC(=O)[C@@H]2C[C@@H](F)CN2C(=O)Cn2cc(C(C)=O)c3ccccc23)c1
Show InChI InChI=1S/C28H31ClF2N3O6P/c1-4-39-41(38,40-5-2)20-10-18(27(31)23(29)12-20)13-32-28(37)25-11-19(30)14-34(25)26(36)16-33-15-22(17(3)35)21-8-6-7-9-24(21)33/h6-10,12,15,19,25H,4-5,11,13-14,16H2,1-3H3,(H,32,37)/t19-,25+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<1.00E+3n/an/an/an/an/an/a



Achillion Pharmaceuticals

US Patent


Assay Description
Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...


US Patent US9758537 (2017)

More data for this
Ligand-Target Pair