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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Factor D' and Ligand = 'BDBM340263'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Factor D


(Homo sapiens (Human))
BDBM340263
PNG
((2S,3aR,7aR)-1-(2-(3- acetyl-6-hydroxy-1H- indol-1...)
Show SMILES CC(=O)c1cn(CC(=O)N2[C@@H]3CCCC[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(O)ccc12
Show InChI InChI=1S/C28H29ClFN3O4/c1-16(34)21-14-32(24-12-19(35)9-10-20(21)24)15-26(36)33-23-8-3-2-5-17(23)11-25(33)28(37)31-13-18-6-4-7-22(29)27(18)30/h4,6-7,9-10,12,14,17,23,25,35H,2-3,5,8,11,13,15H2,1H3,(H,31,37)/t17-,23-,25+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



Achillion Pharmaceuticals

US Patent


Assay Description
Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...


US Patent US9758537 (2017)

More data for this
Ligand-Target Pair