BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Factor D' and Ligand = 'BDBM340267'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Factor D


(Homo sapiens (Human))
BDBM340267
PNG
(US9758537, Compound 70 | ethyl 3-(9-(2-((2S,4R)- 2...)
Show SMILES CCOC(=O)CC(=O)N1CCc2c(C1)n(CC(=O)N1C[C@H](F)C[C@H]1C(=O)NCc1cccc(Cl)c1F)c1ccccc21
Show InChI InChI=1S/C30H31ClF2N4O5/c1-2-42-28(40)13-26(38)35-11-10-21-20-7-3-4-9-23(20)36(25(21)16-35)17-27(39)37-15-19(32)12-24(37)30(41)34-14-18-6-5-8-22(31)29(18)33/h3-9,19,24H,2,10-17H2,1H3,(H,34,41)/t19-,24+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



Achillion Pharmaceuticals

US Patent


Assay Description
Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...


US Patent US9758537 (2017)

More data for this
Ligand-Target Pair