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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Factor D' and Ligand = 'BDBM340278'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Factor D


(Homo sapiens (Human))
BDBM340278
PNG
((2S,4R)-1-(2-(3-acetyl- 5-(1-(1,3- dioxoisoindolin...)
Show SMILES CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(Br)n2)c2ccc(cc12)C1(CC1)N1C(=O)c2ccccc2C1=O
Show InChI InChI=1S/C33H27BrFN5O5/c1-18(41)24-16-38(17-29(42)39-15-20(35)14-26(39)30(43)37-28-8-4-7-27(34)36-28)25-10-9-19(13-23(24)25)33(11-12-33)40-31(44)21-5-2-3-6-22(21)32(40)45/h2-10,13,16,20,26H,11-12,14-15,17H2,1H3,(H,36,37,43)/t20-,26+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<1.00E+3n/an/an/an/an/an/a



Achillion Pharmaceuticals

US Patent


Assay Description
Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...


US Patent US9758537 (2017)

More data for this
Ligand-Target Pair