BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Factor D' and Ligand = 'BDBM340285'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Factor D


(Homo sapiens (Human))
BDBM340285
PNG
(1-(2-((2S,4R)-2-(2'- chloro-2,3',5'- trifluorobiph...)
Show SMILES NC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(c2F)-c2cc(F)cc(F)c2Cl)c2ccccc12
Show InChI InChI=1S/C27H20ClF4N5O3/c28-23-17(8-13(29)9-18(23)31)15-5-3-6-19(24(15)32)34-27(40)21-10-14(30)11-36(21)22(38)12-37-20-7-2-1-4-16(20)25(35-37)26(33)39/h1-9,14,21H,10-12H2,(H2,33,39)(H,34,40)/t14-,21+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<1.00E+3n/an/an/an/an/an/a



Achillion Pharmaceuticals

US Patent


Assay Description
Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...


US Patent US9758537 (2017)

More data for this
Ligand-Target Pair