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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Factor D' and Ligand = 'BDBM340288'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Factor D


(Homo sapiens (Human))
BDBM340288
PNG
((2S,4R)-1-(2-(3-acetyl- 4-cyano-1H-indol-1- yl)ace...)
Show SMILES CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(c2F)-c2ccccc2Cl)c2cccc(C#N)c12
Show InChI InChI=1S/C30H23ClF2N4O3/c1-17(38)22-15-36(25-11-4-6-18(13-34)28(22)25)16-27(39)37-14-19(32)12-26(37)30(40)35-24-10-5-8-21(29(24)33)20-7-2-3-9-23(20)31/h2-11,15,19,26H,12,14,16H2,1H3,(H,35,40)/t19-,26+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<1.00E+3n/an/an/an/an/an/a



Achillion Pharmaceuticals

US Patent


Assay Description
Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...


US Patent US9758537 (2017)

More data for this
Ligand-Target Pair