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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Factor D' and Ligand = 'BDBM340300'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Factor D


(Homo sapiens (Human))
BDBM340300
PNG
((2S,4R)-1-(2-(3-acetyl- 7-(6-chloropyridin-3- yl)-...)
Show SMILES CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(c2F)-c2ccccc2Cl)c2c(cccc12)-c1ccc(Cl)nc1
Show InChI InChI=1S/C34H26Cl2F2N4O3/c1-19(43)26-17-41(33-22(7-4-9-25(26)33)20-12-13-30(36)39-15-20)18-31(44)42-16-21(37)14-29(42)34(45)40-28-11-5-8-24(32(28)38)23-6-2-3-10-27(23)35/h2-13,15,17,21,29H,14,16,18H2,1H3,(H,40,45)/t21-,29+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<1.00E+3n/an/an/an/an/an/a



Achillion Pharmaceuticals

US Patent


Assay Description
Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...


US Patent US9758537 (2017)

More data for this
Ligand-Target Pair