BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Factor D' and Ligand = 'BDBM340309'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Factor D


(Homo sapiens (Human))
BDBM340309
PNG
(1-(2-((2S,4R)-2-(3-(4- chloro-1H- benzo[d]imidazol...)
Show SMILES NC(=O)c1nn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(c2F)-c2ccc3[nH]cnc3c2Cl)c2ccccc12
Show InChI InChI=1S/C28H22ClF2N7O3/c29-23-15(8-9-19-26(23)34-13-33-19)16-5-3-6-18(24(16)31)35-28(41)21-10-14(30)11-37(21)22(39)12-38-20-7-2-1-4-17(20)25(36-38)27(32)40/h1-9,13-14,21H,10-12H2,(H2,32,40)(H,33,34)(H,35,41)/t14-,21+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a<1.00E+3n/an/an/an/an/an/a



Achillion Pharmaceuticals

US Patent


Assay Description
Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...


US Patent US9758537 (2017)

More data for this
Ligand-Target Pair