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Found 2 Enz. Inhib. hit(s) with Target = 'Fatty acid synthase' and Ligand = 'BDBM269306'
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM269306((R)-2-(4-(benzo[d]oxazol-2-yl)-2-fluorophenyl)-1-(...)
Affinity DataIC50:  191nMAssay Description:In this assay, inhibition of FASN activity is measured using 3H-acetyl-CoA and malonyl-CoA as substrates. 3H-Acetyl CoA is converted to 3H-palmitate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM269306((R)-2-(4-(benzo[d]oxazol-2-yl)-2-fluorophenyl)-1-(...)
Affinity DataIC50:  191nMpH: 7.5 T: 2°CAssay Description:In this assay, inhibition of FASN activity is measured using 3H-acetyl-CoA and malonyl-CoA as substrates. 3H-Acetyl CoA is converted to 3H-palmitate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent