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Found 5 Enz. Inhib. hit(s) with Target = 'Fatty acid synthase' and Ligand = 'BDBM50241313'
TargetFatty acid synthase(Homo sapiens (Human))
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50241313((5R)-4-hydroxy-3,5-dimethyl-5-[(1E)-2-methylbuta-1...)
Affinity DataIC50:  9.98E+4nMAssay Description:Inhibitory concentration against purified human fatty acid synthase activity in ZR-75-1 breast cancer cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50241313((5R)-4-hydroxy-3,5-dimethyl-5-[(1E)-2-methylbuta-1...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibitory activity against human FAS1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50241313((5R)-4-hydroxy-3,5-dimethyl-5-[(1E)-2-methylbuta-1...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibitory concentration against purified human fatty acid synthase activity in ZR-75-1 breast cancer cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50241313((5R)-4-hydroxy-3,5-dimethyl-5-[(1E)-2-methylbuta-1...)
Affinity DataIC50: >3.80E+5nMAssay Description:Inhibition of FASN in human HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50241313((5R)-4-hydroxy-3,5-dimethyl-5-[(1E)-2-methylbuta-1...)
Affinity DataIC50: >9.51E+5nMAssay Description:Inhibition of FASN in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed