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Found 3 Enz. Inhib. hit(s) with Target = 'Fatty acid synthase' and Ligand = 'BDBM50426445'
TargetFatty acid synthase(Homo sapiens (Human))
3-V Biosciences

US Patent
LigandPNGBDBM50426445(CHEMBL2322372)
Affinity DataIC50:  130nMAssay Description:The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFatty acid synthase(Homo sapiens (Human))
3-V Biosciences

US Patent
LigandPNGBDBM50426445(CHEMBL2322372)
Affinity DataIC50:  130nMAssay Description:Inhibition of human FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
3-V Biosciences

Curated by ChEMBL
LigandPNGBDBM50426445(CHEMBL2322372)
Affinity DataIC50:  2.95E+3nMAssay Description:Inhibition of rat FASN assessed as release of co-enzyme AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed