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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fatty acid-binding protein 4 (FABP4)' and Ligand = 'BDBM312346'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312346
PNG
(2-[3-(3-Cyclopropyl-[1,2,4]oxadiazol-5-yl)-6-methy...)
Show SMILES CC1CCc2c(C1)sc(NC(=O)C1=C(CCCC1)C(O)=O)c2-c1nc(no1)C1CC1
Show InChI InChI=1S/C22H25N3O4S/c1-11-6-9-15-16(10-11)30-21(17(15)20-23-18(25-29-20)12-7-8-12)24-19(26)13-4-2-3-5-14(13)22(27)28/h11-12H,2-10H2,1H3,(H,24,26)(H,27,28)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 20n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair