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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fatty acid-binding protein 4 (FABP4)' and Ligand = 'BDBM312485'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty acid-binding protein 4 (FABP4)


(Homo sapiens (Human))
BDBM312485
PNG
(2-[6,6-Difluoro-3-(4-isopropyl-thiazol-2-yl)-4,5,6...)
Show SMILES CC(C)c1csc(n1)-c1c(NC(=O)C2=C(CCC2)C(O)=O)sc2CC(F)(F)CCc12
Show InChI InChI=1S/C21H22F2N2O3S2/c1-10(2)14-9-29-18(24-14)16-13-6-7-21(22,23)8-15(13)30-19(16)25-17(26)11-4-3-5-12(11)20(27)28/h9-10H,3-8H2,1-2H3,(H,25,26)(H,27,28)
PDB

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 20n/an/an/an/an/an/a



Hoffman-La Roche Inc.

US Patent


Assay Description
Compounds were profiled for activity against human FABP4 (huFABP4) and/or human FABP5 (huFABP5) in Terbium (Tb) time resolved-fluorescence energy tra...


US Patent US9604977 (2017)

More data for this
Ligand-Target Pair